Follistatin Research Compound
Research Use Only
This product is intended for laboratory research purposes only. It is not intended for human or veterinary use, food, cosmetic, household, or agricultural applications. Not for human consumption.
Overview
Follistatin is a naturally occurring glycoprotein that binds and neutralizes members of the TGF-beta superfamily, particularly activin and myostatin. By sequestering myostatin, follistatin removes the natural brake on muscle growth, making it valuable for muscle biology research.
Mechanism of Action
Follistatin promotes muscle growth through:
- Direct myostatin binding and neutralization
- Activin sequestration
- Relief of TGF-beta pathway inhibition
- Enhanced muscle protein synthesis
- Satellite cell activation
Follistatin Isoforms
| Isoform | Amino Acids | Primary Location |
|---|---|---|
| FS288 | 288 | Tissue-bound |
| FS315 | 315 | Circulating |
| FS344 | Precursor | Cleaved to FS315 |
Research Applications
- Myostatin inhibition studies
- Muscle hypertrophy mechanisms
- TGF-beta pathway research
- Gene therapy vector studies
Handling & Storage
- Store lyophilized protein at -20C or below
- Protect from light
- Reconstitute with sterile buffer
- Aliquot to avoid freeze-thaw cycles