MGF (Mechano Growth Factor) Research Compound
Research Use Only
This product is intended for laboratory research purposes only. It is not intended for human or veterinary use, food, cosmetic, household, or agricultural applications. Not for human consumption.
Overview
MGF (Mechano Growth Factor) is a splice variant of IGF-1 that is expressed in muscle tissue following mechanical stress or damage. The peptide differs from systemic IGF-1 in its C-terminal E domain and plays a specific role in muscle satellite cell activation and the early phases of muscle repair.
Mechanism of Action
MGF acts through unique pathways:
- Satellite cell activation
- Muscle stem cell proliferation
- Expressed in response to mechanical stress
- Distinct from systemic IGF-1Ea
- Local autocrine/paracrine signaling
MGF vs. Systemic IGF-1
| Property | MGF | IGF-1Ea |
|---|---|---|
| Expression | Mechanical stress | Constitutive |
| Primary Action | Satellite cell activation | Myocyte differentiation |
| Half-life | Very short | Short |
| Target | Muscle stem cells | Mature myocytes |
Research Applications
- Satellite cell biology
- Muscle regeneration mechanisms
- Exercise-induced signaling
- Mechanical stress response
Handling & Storage
- Store lyophilized peptide at -20C
- Protect from light
- Reconstitute with bacteriostatic water
- Very short half-life - use promptly