PE-22-28 Research Compound
Research Use Only
This product is intended for laboratory research purposes only. It is not intended for human or veterinary use, food, cosmetic, household, or agricultural applications. Not for human consumption.
Overview
PE-22-28 is a synthetic heptapeptide analog of Spadin, derived from the propeptide region of TREK-1 potassium channels. TREK-1 inhibition has been associated with antidepressant-like effects and enhanced neurogenesis in research models, making PE-22-28 valuable for neuroplasticity and mood research.
Mechanism of Action
PE-22-28 modulates neural function through:
- TREK-1 potassium channel inhibition
- Enhanced neuronal excitability
- BDNF pathway interactions
- Hippocampal neurogenesis effects
- Rapid-acting mechanism
Research Applications
- TREK-1 channel pharmacology
- Neurogenesis studies
- Mood regulation research
- Neuroplasticity mechanisms
Handling & Storage
- Store lyophilized peptide at -20C
- Protect from light and moisture
- Reconstitute with bacteriostatic water
- Reconstituted solution stable at 2-8C for up to 3 weeks