Triptorelin (GnRH) Research Compound
Research Use Only
This product is intended for laboratory research purposes only. It is not intended for human or veterinary use, food, cosmetic, household, or agricultural applications. Not for human consumption.
Overview
Triptorelin is a synthetic GnRH agonist with approximately 100x greater potency than native GnRH. Following initial stimulation, continuous administration leads to pituitary desensitization and suppression of gonadotropins, making it valuable for both stimulation and suppression research protocols.
Mechanism of Action
Triptorelin modulates the HPG axis:
- High-affinity GnRH receptor binding
- Initial LH/FSH surge (flare effect)
- Subsequent receptor downregulation
- Gonadal steroid suppression
Clinical Background
| Application | Mechanism |
|---|---|
| Initial | Stimulation (fertility) |
| Continuous | Suppression (oncology) |
Research Applications
- GnRH receptor pharmacology
- Hormonal suppression studies
- Reproductive axis research
- Prostate cancer models
Handling & Storage
- Store lyophilized peptide at -20C
- Protect from light and moisture
- Reconstitute with bacteriostatic water
- Reconstituted solution stable at 2-8C for up to 4 weeks